A Discord bot that helps you study! Contribute to micropipette/studybot development by creating an account on GitHub.

GitHub - micropipette/studybot: A Discord bot that helps you study!

nzodiazepines. However, recent evidence suggesting the contrary raises concerns about their safety. This review examines current evidence on problematic azapirone use.

Methods: 

This study was conducted in line with the Preferred Reporting Items for Systematic reviews and Meta-Analyses for Scoping Reviews (PRISMA-ScR) guidelines. Major databases, including MEDLINE/PubMed, PsycInfo, and EMBASE, were searched to identify eligible papers. Additional searches were conducted to supplement. Article selection and data extraction were completed by at least 2 independent reviewers.

Results: 

Thirteen reports made up of clinical studies (n = 9) and case reports (n = 4) were included. All abuse liability studies comparing azapirones (buspirone and tandospirone), benzodiazepines, and placebo reported no association of buspirone and tandospirone with key features of problematic use. Conversely, all case reports (n = 4) described problematic use, involving patients with a history of incarceration or substance use disorder (SUD) who insufflated buspirone to achieve a sedative effect.

Conclusions: 

Findings highlight a discrepancy in the primary literature. Specifically, experimental studies conclude that so far, buspirone and tandospirone have a low potential for problematic use. However, more recent case reports document instances of nonprescribed buspirone misuse, particularly among individuals with a history of incarceration or SUD, possibly stemming from a complex interplay of biopsychosocial-behavioral rather than purely pharmacological factors. Further research is needed to guide strategies for preventing problematic azapirone use while ensuring effective anxiety treatment in high-risk populations....

Problematic Use of Buspirone and Tandospirone: A Scoping... : Journal of Addiction Medicine

Listen to Philip Yu on Spotify. Artist · 1.8K monthly listeners.

Philip Yu

See 68 of the best free to download photos, images, and wallpapers by Philip Yu on Unsplash.

Philip Yu (@philipyu) | Unsplash Photo Community

823 Followers, 551 Following, 11 Posts - Philip 🌊 (@study.phil) on Instagram: "ubc med | mac bhsc"

Philip 🌊 (@study.phil) • Instagram photos and videos

posting about anything I find interesting :))

4NSWER

Fall Apart